REVIEW
Katarína VLČKOVÁ, Denisa ČELOVSKÁ: Hypertension mediated organ damage – a compass in the reclassification of the cardiovascular risk    of the hypertensive patients and in the treatment effectiveness assessment
Lukáš ŠEBESTA, Magdaléna JABLONICKÁ, Beata MLADOSIEVIČOVÁ: New possibilities of overcoming the endocrine resistance in patients    with breast cancer
Mária PLIŠOVÁ, Drahomír PALENČÁR, Jozef BEŇUŠKA: Types of metacarpal bone fractures and their treatment
Tatiana KIMÁKOVÁ, Marián BERNADIČ, Ivan UHER, Mariana RAČKOVÁ: Oxidative stress and lifestyle risk factors

CLINICAL STUDY
Nataliia Vasylvna GUBINA, Vasyl Hryhorovych MISHCHUK, Iryna Hryhorivna KUPNOVYTSKA, Halyna O. STUPNITSKA:  Sporadic inflammatory markers and ghrelin levels in patients with early stages of chronic kidney disease against the background of obesity         189
Ivan LISNYY, Olesya ZAKALSKA, Dmytro DMYTRIIEV, Kostiantyn DMYTRIIEV, Oleksandr DOBROVANOV: Pre-emptive analgesia with   nonsteroidal anti-inflammatory drugs. randomized, double-blind placebo-controlled study