SUMMARY
Sepsis is still a clinical condition complicated by high mortality. Early diagnosis and casual treatment are crucial. Urosepsis is defined as sepsis caused by a urogenital tract infection. Urosepsis in adults comprises approximately 25 % of all sepsis cases, and in most cases is due to complicated urinary tract infections. Septic shock is a critical situation, with a reported mortality rate nowadays still ranging from 30 % to 40 %. Urosepsis is in major of cases as a result of infection of urinary tract and obstructed uropathy of the upper urinary tract, by ureterolithiasis as the most common cause. Treatment of urosepsis comprises four major aspects: (i) early diagnosis; (ii) early goal-directed therapy including optimal pharmacodynamic exposure to antimicrobials; (iii) identification and control of the complicating factor in the urinary tract; and (iv) fluid therapy.

Key words: urinary tract infections, urosepsis, urinary tract obstruction, managment for urosepsis, sepsis therapy.

Lek Obz, 2020, 69 (10): 364-368

Michaela MIHAĽOVÁ, Peter CELEC, Ján BREZA

1 Urologická klinika LF UK, SZU a UNB, prednosta Dr. h. c. prof. MUDr. J. Breza, DrSc., MPH, MHA
2 Ústav molekulárnej biomedicíny, LF UK v Bratislave, prednosta doc. MUDr. Ing. RNDr. P. Celec, DrSc., MPH

Michaela MIHAĽOVÁ, Peter CELEC, Ján BREZA: Urosepsis. Lek Obz, 2020, 69 (10): 364-368