Abstract
INTRODUCTION. Stroke is one of the most common causes of mortality and long-term disability worldwide. In a sizeable amount of patients, a certain degree of neurological deficit persists after overcoming it. For this reason, it is necessary to develop therapeutic procedures that would help alleviate the consequences of this disease. Repetitive magnetic stimulation is a non-invasive neurostimulation and neuromodulation technique that uses the induction of a magnetic field to subsequently influence events in the brain in a complex manner. According to available scientific evidence, a supportive effect of repetitive magnetic stimulation can be expected to improve motor functions in patients after stroke.
OBJECTIVE. The presented article was created in the preparation of a research project in which we plan to evaluate the impact of repetitive transcranial magnetic stimulation on the recovery of motor functions in patients after stroke.
MATERIAL AND METHODS. In the second part of our work, concerning repetitive transcranial magnetic stimulation and its therapeutic use in patients after stroke, we deal in more detail with the results of clinical trials in this area and practical aspects in the development of clinical trial protocols.
RESULTS. The results of studies investigating the effect of repetitive transcranial magnetic stimulation on motor deficit in patients after stroke are highly heterogeneous. This may be due to significant differences in the therapeutic protocols used and the different timings of the intervention.
CONCLUSIONS. Repetitive transcranial magnetic stimulation appears to be a safe and effective method for improving motor functions in patients after stroke. Appropriate intervention timing and optimal parameters of applied repetitive transcranial magnetic stimulation must be revealed in future prospective studies (Ref. 51). Text in PDF www.lekarskyobzor.sk.
KEY WORDS: stroke, repetitive transcranial magnetic stimulation.
Lek Obz 2022, 71 (9): 331-337
Katarína VALOVIČOVÁ 1, Pavel ŠIARNIK 1, Igor RIEČANSKÝ 2,3, Stanislava KLOBUCKÁ 4, Eva VASKÁ 5, Marek SÝKORA 1,6, Peter TURČÁNI 1, Branislav KOLLÁR 1
1 I. neurologická klinika Lekárskej fakulty Univerzity Komenského v Bratislave a Univerzitnej nemocnice Bratislava, Bratislava, prednosta prof. MUDr. P. Turčáni, PhD.
2 Centrum experimentálnej medicíny Slovenskej akadémie vied, Bratislava, riaditeľka doc. RNDr. O. Pecháňová, DrSc.
3 Psychiatrická klinika Slovenskej zdravotníckej univerzity v Bratislave, Bratislava, prednostka doc. MUDr. Ľ. Forgáčová, PhD.
4 Rehabilitačné centrum Harmony, n.o., Bratislava, primárka MUDr. S. Klobucká, PhD.
5 Fakulta zdravotníckych vied, Univerzita sv. Cyrila a Metoda, Trnava, dekan prof. MUDr. Ľ. Gašpar, CSc.
6 Neurological Intensive Care Unit & Stroke Unit, St. John of God Hospital, Viedeň, prednosta Prim. Univ. Prof. dr. W. Lang
CITE:
VALOVIČOVÁ K., ŠIARNIK P., RIEČANSKÝ I., KLOBUCKÁ S., VASKÁ E., SÝKORA M., TURČÁNI P., KOLLÁR B.: Therapeutic use of repetitive transcranial magnetic stimulation in pacients after stroke. Part II: Clinical studies. Lek Obz 2022, 71 (9): 331-337
